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PIER PIER B PIER C PIER M PIER Letters
2016-04-13
Metamaterial Antenna Arrays for Improved Uniformity of Microwave Hyperthermia Treatments
By
David Vrba,

    Dr. David Vrba

    Department of Electromagnetic Field

    Czech Technical University in Prague

    Czech Republic

    Homepage

Dario Rodrigues,

    Prof. Dario Rodrigues

    Department of Radiation Oncology

    University of Maryland School of Medicine

    United States

    Homepage

Jan Vrba (Jr.),

    Mr. Jan Vrba (Jr.)

    Faculty of Biomedical Engineering

    Czech Technical University in Prague

    Czech Republic

    Homepage

Paul R. Stauffer

    Prof. Paul R. Stauffer

    Radiation Oncology Department

    Thomas Jefferson University

    USA

    Homepage

Progress In Electromagnetics Research, Vol. 156, 1-12, 2016
doi:10.2528/PIER16012702
Abstract
Current microwave hyperthermia applicators are not well suited for uniform heating of large tissue regions. The objective of this research is to identify an optimal microwave antenna array for clinical use in hyperthermia treatment of cancer. For this aim we present a novel 434 MHz applicator design based on a metamaterial zeroth order mode resonator, which is used to build larger array configurations. These applicators are designed to effectively heat large areas extending deep below the body surface and in this work they are characterized with numerical simulations in ahomogenous muscle tissue model. Their performance is evaluated using three metrics: radiation pattern-based Effective Field Size (EFS), temperature distribution-based Therapeutic Thermal Area (TTA), and Therapeutic Thermal Volume (TTV) reaching 41-45°C. For 2×2 and 2×3 array configurations, the EFS reaching > 25% of maximum SAR in the 3.5 cm deep plane is 100% and 91% of the array aperture area, respectively. The corresponding TTA for these arrays is 95% and 86%, respectively; and the TTV attaining > 41°C is over 85% of the aperture area toa depth of over 3 cm in muscle, using either array configuration. With theoretical heating performance exceeding that of existing applicators, these new metamaterial zero order resonator arrays show promise for future applications in large area superficial hyperthermia.
Citation
David Vrba, Dario Rodrigues, Jan Vrba (Jr.), and Paul R. Stauffer, "Metamaterial Antenna Arrays for Improved Uniformity of Microwave Hyperthermia Treatments," Progress In Electromagnetics Research, Vol. 156, 1-12, 2016.
doi:10.2528/PIER16012702
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